The Buffalo Bills powered through the San Francisco 49ers with a commanding 35-10 win in a snowy Week 13 matchup. Quarterback Josh Allen led the charge with four touchdowns, while running back James Cook dazzled with a 120-yard game, including a thrilling 65-yard dash. The 49ers struggled under the pressure, marred by missed field goals, turnovers, and a devastating injury to star Christian McCaffrey.
Buffalo’s well-rounded performance solidified their playoff positioning, while San Francisco faces critical questions after this humbling defeat.